Validation of the function of PD-1 in the development of tumor and autoimmune disease. Trace the functional cells in the development of tumor and autoimmune disease by the expression of EGFP.
Function research of genes. This Tgfb1CKO model is an efficient tool to study the Tgfb1 gene functions in various tissue and cells when crossed with different tissue and cell specific Cre expressing mice.
Function research of genes. Deletion of specific groups of cells