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PD-L1/LAG-3 bispecific antibody enhances tumor-specific immunity

Used in this study: B-hPD-L1/hLAG3 mice. Part Author's Institute: Innovent Biologics (Suzhou) Co.,Ltd.

Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy

Used in this study: B-hPD-1 mice. Part Author's Institute: Macau University of Science and Technology.

Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1.

Used in this study: B-hPD-1/hPD-L1 mice. Part Author's Institute: Arbutus Biopharma Inc.

Tislelizumab uniquely binds to the CC' loop of PD-1 with slow-dissociated rate and complete PD-L1 blockage.

Used in this study: B-hPD-1 mice. Part Author's Institute: BeiGene (Beijing) Co., Ltd.

Anticancer immunity induced by a synthetic tumor-targeted CD137 agonist

Used in this study: B-h4-1BB mice. Part Author's Institute: Bicycle Therapeutics.

Preclinical efficacy and toxicity studies of a highly specific chimeric anti-CD47 antibody.

Used in this study: B-hSIRPA/hCD47 mice.Part Author's Institute: Shanghai ChemPartner Co., Ltd.

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