B-hF11R mice
| Strain Name | C57BL/6N-F11rtm1(F11R)Bcgen/Bcgen | Common Name | B-hF11R mice |
| Background | C57BL/6N | Catalog number |
112164 |
| Aliases |
F11R, JAM, JAM1, JAMA, JCAM, KAT, PAM-1 |
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Model validation
Protein expression analysis of F11R(JAM1) in platelet
Protein expression analysis of F11R(JAM1) in T cells, B cells and Monocytes of splenocytes
Protein expression analysis of F11R(JAM1) in NK cells, dendritic cells and Macrophages of splenocytes
Protein expression analysis of F11R(JAM1) in Stem cells of bone marrow
Protein expression analysis of F11R(JAM1) in Endothelial cells of lung
Strain specific F11R expression analysis in homozygous B-hF11R mice by flow cytometry. Platelet were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hF11R mice (H/H), and analyzed by flow cytometry with species-specific anti-F11R antibody. Mouse F11R was detectable in platelet of wild-type C57BL/6 mice. Human F11R was exclusively detectable in platelet of homozygous B-hF11R mice but not in wild-type C57BL/6 mice.
Strain specific F11R expression analysis in homozygous B-hF11R mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hF11R mice (H/H), and analyzed by flow cytometry with species-specific anti-F11R antibody. Mouse F11R was not detectable in T cells (A), B cells (B) and monocytes (C) of wild-type C57BL/6 mice. Human F11R was not detectable in T cells (A), B cells (B) and was detectable monocytes (C) of homozygous B-hF11R mice.
Strain specific F11R expression analysis in homozygous B-hF11R mice by flow cytometry. Splenocytes were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hF11R mice (H/H), and analyzed by flow cytometry with species-specific anti-F11R antibody. Mouse F11R was detectable in NK cells (A), dendritic cells (B) and macrophages (C) of wild-type C57BL/6 mice. Human F11R was exclusively detectable in NK cells (A), dendritic cells (B) and macrophages (C) of homozygous B-hF11R mice but not in wild-type C57BL/6 mice.
Strain specific F11R expression analysis in homozygous B-hF11R mice by flow cytometry. Bone marrow were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hF11R mice (H/H), and analyzed by flow cytometry with species-specific anti-F11R antibody. Mouse F11R was detectable in stem cells of wild-type C57BL/6 mice. Human F11R was exclusively detectable in stem cells of homozygous B-hF11R mice but not in wild-type C57BL/6 mice.
Strain specific F11R expression analysis in homozygous B-hF11R mice by flow cytometry. Lung were collected from wild-type C57BL/6 mice (+/+) and homozygous B-hF11R mice (H/H), and analyzed by flow cytometry with species-specific anti-F11R antibody. Mouse F11R was detectable in endothelial cells of wild-type C57BL/6 mice. Human F11R was exclusively detectable in endothelial cells of homozygous B-hF11R mice but not in wild-type C57BL/6 mice.
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