Reporter line that can be crossed with Cre-expressing strains. In presence of Cre, the floxed "stop" upstream of the TdTomato gene is deleted allowing expression of the red fluorescent TdTomato protein.
Validation of the expression and function of Plaur in diseases
Validation of the function of Cd155 in the development of tumor disease
Validation of the function of PD-1 in the development of tumor and autoimmune disease. Trace the functional cells in the development of tumor and autoimmune disease by the expression of EGFP.
Function research of genes. Deletion of specific groups of cells
Function research of genes .This model is an efficient tool in tracking the expression pattern of IL17A with EGFP fluorescence.
This CAG-tdTomato model is an efficient tool to study the tissue specification of Cre mice, when cross with the Cre mice.