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Animal&Cell Models
Humanized animal models
Humanization of immune checkpoints
Text
B-hCD3EDG/hCD70 mice
Database
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Strain Name C57BL/6-Cd3etm1(CD3E)Bcgen Cd3dtm1(CD3D)Bcgen Cd3gtm1(CD3G)Bcgen Cd70tm1(CD70)Bcgen/Bcgen Common Name  B-hCD3EDG/hCD70 mice
Background C57BL/6 Catalog number 112768
Related Genes 

CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A; 

IMD18, T3E, TCRE; CD3-DELTA, IMD19, T3D

Model validation
该动物由B-hCD3EDG mice(110039)和B-hCD70 mice(110770)交配获得,可参考相关单基因产品验证数据。
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