B-hTL1A mice
| Strain Name |
C57BL/6N-Tnfsf15tm2(TNFSF15)Bcgen/Bcgen |
Common Name | B-hTL1A mice |
| Background | C57BL/6 | Catalog number | 111997 |
|
Aliases |
TNFSF15, TL1, TL1A, TNLG1B, VEGI, VEGI192A, TNF superfamily member 15 |
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Model validation
mRNA expression analysis
Protein expression analysis
Strain specific analysis of TL1 gene expression in wild type (WT) mice and B-hTL1A mice by RT-PCR. Mouse Tl1a mRNA was detectable only in lung of WT mice (+/+). Human TL1A mRNA was detectable only in homozygous B-hTL1A mice (H/H) but not in WT mice (+/+).
Strain specific TL1A expression analysis in homozygous B-hTL1A mice by flow cytometry. Lung endothelial cells were collected from wild type (WT) mice (+/+) and homozygous B-hTL1A mice (H/H), and analyzed by flow cytometry with anti-TL1A antibody. TL1A was detectable in WT mice (+/+) and homozygous B-hTL1A mice (H/H) due to the cross-reactivity of antibodies.
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