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Animal&Cell Models

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Text

B-hLGALS3BP mice

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Strain Name	C57BL/6N-Lgals3bp^{tm1(LGALS3BP)Bcgen}/Bcgen	Common Name	B-hLGALS3BP mice
Background	C57BL/6N	Catalog number	112343
Aliases	LGALS3BP(90K, BTBD17B, CyCAP, M2BP, MAC-2-BP, TANGO10B, gp90)

Model validation

mRNA and protein expression analysis

Strain specific analysis of LGALS3BP gene expression in wild-type mice and B-hLGALS3BP mice by RT-PCR. Mouse Lgals3bp mRNA was detectable in small intestine of wild-type mice (+/+). Human LGALS3BP mRNA was detectable only in homozygous B-hLGALS3BP mice(H/H) but not in wild-type C57BL/6 mice.

Strain specific LGALS3BP protein expression analysis in homozygous B-hLGALS3BP mice by ELISA. Serum was collected from wild-type mice (+/+) and homozygous B-hLGALS3BP mice (H/H), and analyzed by ELISA with species-specific LGALS3BP ELISA kit. Human LGALS3BP was exclusively detectable in homozygous B-hLGALS3BP mice but not in wild-type mice.